Transaction management across data stores

Companies have evolved from a world where they only had SQL databases to a world where they use different kinds of data stores, such as key­value data stores, document­oriented data stores and graph databases. The reason why they have started to introduce this diversity of persistency models is because different NoSQL technologies bring different data models with associated query languages and/or APIs. However, they are confronted now with a problem in which they have the data scattered across different data stores. This problem lies in that when a business action requires to update the data, the data reside in different data stores, and they are subject to inconsistencies in the event of failure and/or concurrent access. These inconsistencies appear due to the lack of transactional consistency that was guaranteed in traditional SQL databases but is not guaranteed either within the NoSQL data stores or across data stores and databases. CoherentPaaS comes to remedy this need. CoherentPaaS provides an ultra­scalable transactional management layer that can be integrated with any data store with multi­ versioning capabilities. The layer has been integrated with six different data stores, three NoSQL data stores and three SQL­like databases. In this paper, we describe this generic ultra­scalable transactional management layer and focus on its API and how it can be integrated in different ways with different data stores and databases

A scalable SIEM correlation engine and its application to the Olympic Games IT infrastructure

The security event correlation scalability has become a major concern for security analysts and IT administrators when considering complex IT infrastructures that need to handle gargantuan amounts of events or wide correlation window spans. The current correlation capabilities of Security Information and Event Management (SIEM), based on a single node in centralized servers, have proved to be insufficient to process large event streams. This paper introduces a step forward in the current state of the art to address the aforementioned problems. The proposed model takes into account the two main aspects of this ?eld: distributed correlation and query parallelization. We present a case study of a multiple-step attack on the Olympic Games IT infrastructure to illustrate the applicability of our approach

CumuloNimbo: parallel-distributed transactional processing

CumuloNimbo aims at solving the lack of scalability of transactional applications that represent a large fraction of existing applications. CumuloNimbo aims at conceiving, architecting and developing a transactional, coherent, elastic and ultra scalable Platform as a Service. Its goals are: Ultra scalable and dependable, able to scale from a few users to many millions of users while at the same time providing continuous availability; Support transparent migration of multi-tier applications (e.g. Java EE applications, relational DB applications, etc.) to the cloud with automatic scalability and elasticity. Avoid reprogramming of applications and non-transparent scalability techniques such as sharding. Support transactions for new data stores such as cloud data stores, graph databases, etc.The main challenges are: Update ultrascalability (million update transactions per second and as many read-only transactions as needed). Strong transactional consistency. Non-intrusive elasticity. Inexpensive high availability. Low latency. CumuloNimbo goes beyond the state of the art by scaling transparently transactional applications to very large rates without sharding, the current practice in Today?s cloud. In this paper we describe CumuloNimbo architecture and its performance

Inhomogeneity detection in phytoplankton time series using multivariate analyses

Phytoplankton communities have long been used as water quality indicators within environmental policies. This has fostered the development of national and international phytoplankton monitoring programs, but these networks are subject to sources of uncertainty due to laboratory issues. Nevertheless, studies regarding the interference associated with these aspects are not well-documented. Hence, a long time series (2003-2015) from the Basque continental shelf (southeastern Bay of Biscay) was analyzed to evaluate the uncertainty given by laboratory strategies when studying phytoplankton variability. Variability in phytoplankton communities was explained not only by environmental conditions but also by changes in fixatives (glutaraldehyde and acidic Lugol's solution) and laboratory staff. Based on Bray-Curtis distances, phytoplankton assemblages were found to be significantly dissimilar according to the effect of changes in the specialist handling the sample and the employed fixative. The pair-wise permutational multivariate analysis of variance (PERMANOVA) showed significant differences between the two fixatives utilized and also between the three taxonomists involved. Thus, laboratory-related effects should be considered in the study of phytoplankton time series.The data for this study were obtained from the project "Program for the monitoring and assessment of the ecological status of transitional and coastal waters of the Basque Country" funded by URA, the Basque Water Agency, through a convention with AZTI. This work was supported by the project "IM17MUSSELS". The participation of O. Muniz was funded by a grant from the Department of Economic Development and Competitiveness of the Basque Government (BOPV num. 201; 2013/4467). This paper is contribution number 956 from AZTI (Marine Research Division). We also thank Proof-Reading-Service for their great professional proof reading and editing service, as well as the anonymous reviewers for their comments and suggestions

Assessment of a Sheltered Euhaline Area of the Southeastern Bay of Biscay to Sustain Bivalve Production in Terms of Phytoplankton Community Composition

This study describes the phytoplankton community in sheltered euhaline waters of the Basque coast (southeastern Bay of Biscay). Phytoplankton composition, cell size, abundance, biomass and the presence of potentially toxic taxa, together with chlorophyll a, nutrients and hydrographic and optical conditions were measured, from August 2016 to August 2017, in the Mutriku port, with the main aim of assessing the suitability of the phytoplankton community as a food resource for bivalves. The water column in Mutriku showed the typical environmental conditions of Basque marine waters, with no significant nutrient enrichment caused by anthropogenic pressures. Haptophytes represented the greatest contribution to cell abundance (31-47%), and diatoms were the dominant group in terms of biomass (52-79%),which could favour mussel growth due to their high fatty acid content. In addition, the size structure of the phytoplankton community was suitable for mussel ingestion, since the predominant cell size was 2-20 mu m. Regarding toxic phytoplankton, the genera that pose a risk for human health and those that affect negatively mussel physiology and survival were considered. Altogether, ten toxic phytoplankton taxa were identified, contributing in less than 5% to the total cell abundance of Mutriku. However, median chlorophyll a concentration was low (0.5 mu g L-1), reflecting the oligotrophic conditions of the area. Therefore, even if the composition of the phytoplankton community could be favourable for bivalve aquaculture, biomass values are low compared to other zones of bivalve productionThis study was partially supported by the project EGRECOST CALIDAD -Control de Calidad de Aguas Cultivos Marinos (Departamento de Desarrollo Economico e Infraestructuras del Gobierno Vasco) and the project PPG17/67 funded by the University of the Basque Country (UPV/EHU). J. Bilbao was funded by a grant from the University of the Basque Country (UPV/EHU -PIF 18/306). This paper is contribution number 991 from AZTI (Marine Research Division

The oncolytic adenovirus VCN-01 promotes anti-tumor effect in primitive neuroectodermal tumor models

Last advances in the treatment of pediatric tumors has led to an increase of survival rates of children affected by primitive neuroectodermal tumors, however, still a significant amount of the patients do not overcome the disease. In addition, the survivors might suffer from severe side effects caused by the current standard treatments. Oncolytic virotherapy has emerged in the last years as a promising alternative for the treatment of solid tumors. In this work, we study the anti-tumor effect mediated by the oncolytic adenovirus VCN-01 in CNS-PNET models. VCN-01 is able to infect and replicate in PNET cell cultures, leading to a cytotoxicity and immunogenic cell death. In vivo, VCN-01 increased significantly the median survival of mice and led to long-term survivors in two orthotopic models of PNETs. In summary, these results underscore the therapeutic effect ofVCN-01 for rare pediatric cancers such as PNETs, and warrants further exploration on the use of this virus to treat them

Guided weekly reflection papers: a strategy for Achieving academic goals

Rapid changes in innovative teaching need multidisciplinary efforts to accomplish a variety of goals through a collaborative tool which inspires and stimulates the students to learn and use the knowledge in a more a critical way. In this context, our team of lecturers concerned by educational innovation had carried out during three academic years a learning tool based on “Weekly Reflection Papers” (WRP). With the experience gained in this process we have implemented an essential modification in the procedure in order to improve the teaching-learning process. The goal of this communication is to show the development of the initial tool and how it has been changed until the actual proposal called Guided Weekly Reflection Papers” (GWRP)

Improving learning environment at different academic Levels throughout guided weekly reflection papers

A group of lecturers from different teaching areas at Alcalá University concern by Innovative Education had implemented during four academic years a learning tool based on “reflective weekly papers”. With the experience gained in this process we have carried out an essential modification in the procedure which provides the students the possibility of a more active and participative learning called Guided Weekly Reflective Papers. In this communication we present the adaptation of this educational method for the first time as a valuable strategy for improving the learning environment in secondary schools, as an extension of its implementation at the University level and as a contribution to the integral formation and meaningful learning of the secondary level students

Guided Weekly Reflection Papers

The experience gained by our team of educational innovation with the implementation of the “Weekly Reflection Papers” has led us to diversify and make more flexible the employed methodology. The modified tool, applied during the academic year 2010-2011, was called “Guided Weekly Reflection Papers”. The aim of this modification has been the development of certain abilities and skills of the students, with particular emphasis on their ability to integrate, review and apply knowledge in a critical and reflective way. The professors guide the student´s work through a series of questions on which the students must apply the most significant concepts studied each week, to prove the acquisition of such aptitudes and skills

Guided Weekly Reflection Papers

The experience gained by our team of educational innovation with the implementation of the “Weekly Reflection Papers” has led us to diversify and make more flexible the employed methodology. The modified tool, applied during the academic year 2010-2011, was called “Guided Weekly Reflection Papers”. The aim of this modification has been the development of certain abilities and skills of the students, with particular emphasis on their ability to integrate, review and apply knowledge in a critical and reflective way. The professors guide the student´s work through a series of questions on which the students must apply the most significant concepts studied each week, to prove the acquisition of such aptitudes and skills